Levipil Injection is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it.
Levipil Injection is given as an infusion (slow drip) into a vein under the supervision of a healthcare professional. It is generally used for short-term control of seizures when treatment with oral medication is not feasible (eg. when the patient is unconscious). You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. Your doctor is likely to prescribe you oral medicines for long-term seizure control, after treatment with this injection has been completed.
Some common side effects of this medicine include dizziness, headache, infection, irritation, nasopharyngitis, sleepiness, aggressive behavior, and decreased appetite. You may also experience behavioral changes, aggressive behavior, irritation, agitation, etc. Side effects are more common during the first few days and usually lessen as your body gets used to the medicine. Most of these side effects do not need medical attention, but some of them can be serious. Let your doctor know right away if you have developed an allergic reaction (hives, itching, weakness, dizziness, difficulty in breathing, or swelling of face, tongue, and throat), a skin rash, or persistent behavioral changes like confusion, forgetfulness, feeling irritable, increased aggression or hostility. There may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.
Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. Avoid alcohol while taking this medicine, as it may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested periodically while taking this medicine.
BENEFITS OF LEVIPIL INJECTION
In Treatment of Epilepsy/Seizures
Levipil Injection belongs to a group of medicines called anticonvulsants (or anti-epileptics). It works by slowing down electrical signals in the brain which cause seizures (fits). This medicine can be used to control various types of seizures—myoclonic, partial-onset, and primary generalized tonic-clonic (or grand mal). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. You should continue taking it even if you feel well and are not having any seizures. Missing doses may trigger a seizure. Do not stop using this medicine until your doctor advises you.
HOW TO USE LEVIPIL INJECTION
Your doctor or nurse will give you this medicine. Kindly do not self administer.
HOW LEVIPIL INJECTION WORKS
Levipil Injection is an antiepileptic medication. It works by attaching to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.
It is unsafe to consume alcohol with Levipil Injection.
CONSULT YOUR DOCTOR
Levipil Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Levipil Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the baby for sleepiness and adequate weight gain.
Levipil Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Levipil Injection should be used with caution in patients with kidney disease. Dose adjustment of Levipil Injection may be needed. Please consult your doctor.
Levipil Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Levipil Injection may not be needed in these patients. Please consult your doctor.
However, a lower dose may be advised in patients with severe liver disease.
Interaction with drugs
This medicine may interact with anti-anxiety or antiepileptic medicines (carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), acidity medicine (cimetidine), drugs to treat chronic alcoholism (disulfiram), anti-tuberculosis drug (rifampicin), anti-Parkinson’s drug (levodopa), and asthma drugs (theophylline), uricosurics (probenecid).
WHAT IF YOU FORGET TO TAKE LEVIPIL INJECTION?
If you miss a dose of Levipil Injection, get the injection as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Levipil
- Decreased appetite
- Behavioral changes
- Aggressive behavior
- Nasopharyngitis (inflammation of the throat and nasal passages)
Q. Will the use of Levipil Injection affect my fertility?
Levipil Injection is not known to affect fertility in males or females. However, talk to your doctor if you are facing fertility issues during the treatment with this medicine.
Q. Can the use of Levipil Injection cause sleepiness?
Yes, Levipil Injection can make you feel sleepy. Therefore, during the initial phase of treatment, avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities until you know how this medicine affects you.
Q. I have gained weight since I started taking Levipil Injection. Is it because of Levipil Injection? What should I do?
Weight gain is an uncommon side effect of Levipil Injection. However, the response may vary from person to person. To prevent weight gain you should take a healthy balanced diet, avoid snacking, cut down on high-calorie food items, include more vegetables and fruits in your diet, and exercise regularly. If you still have issues with your weight, consult your doctor.
Q. How long does Levipil Injection take to show its effect?
Levipil Injection may take a few weeks to start working properly since the dose is increased slowly. Your seizures may continue until Levipil Injection starts working completely.
Q. For how long do I need to take Levipil Injection?
You should continue to take Levipil Injection for as long as your doctor advises you to. Do not stop taking it suddenly because this may increase the frequency of seizures which may be difficult to control.
Q. Can I drink alcohol with Levipil Injection?
Yes, you may drink alcohol while taking Levipil Injection. Alcohol itself does not affect the way Levipil Injection works. However, alcohol can increase the sleepiness or dizziness that occur as side effects of Levipil Injection in some individuals. Therefore, you should avoid alcohol while taking Levipil Injection until you know how it affects you.
Q. Will I get addicted to Levipil Injection if I use it for a long time?
No, Levipil Injection is not habit-forming. No physical or psychological dependence has been reported with Levipil Injection. Consult your doctor if you experience any side effects.
Q. What symptoms can occur if someone takes an excess of Levipil Injection?
Taking an excess of Levipil Injection may cause sleepiness, agitation, aggression, a decrease of alertness, inhibition of breathing, and even a state of coma. In case of an overdose, immediate medical care should be provided to the patient in a nearby hospital.
Always read the patient information leaflet before commencing treatment.
Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.