SKU: AH_CH_DB_7998 Category:

Generic :  Metformin Hydrochloride (500mg)

Treatment : Diabetes Mellitus Type 2

Pack size  : 15 (Tablet)

Manufacturer : Lupin Ltd

Made In : INDIA



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Gluconorm SR 500mg Tablet is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Gluconorm SR 500mg Tablet is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.



In Treatment of Type 2 diabetes mellitus

Gluconorm SR 500mg Tablet belongs to a class of medicines called biguanides. It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body’s sensitivity to insulin.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.



Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gluconorm SR 500mg Tablet is to be taken with food.



Gluconorm SR 500mg Tablet is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body’s sensitivity to insulin.





It is unsafe to consume alcohol with Gluconorm SR 500mg Tablet.


Gluconorm SR 500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Gluconorm SR 500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.


Gluconorm SR 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gluconorm SR 500mg Tablet may be needed. Please consult your doctor.
Use of Gluconorm SR 500mg Tablet is, however, not recommended in patients with severe kidney disease.


Gluconorm SR 500mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.


Interaction with drugs

Using the below medicines along with Gluconorm SR Tablet may reduce the efficacy or cause side effects.

  • Methylprednisolone : (SERIOUS)
  • Collagen Peptide : (SERIOUS)
  • Ranitidine : (SERIOUS)
  • Betamethasone : (SERIOUS)
  • Propranolol : (SERIOUS)
  • Deflazacort : (SERIOUS)
  • Escitalopram Oxalate : (SERIOUS)
  • Paroxetine : (SERIOUS)
  • Pancreatin : (SERIOUS)



If you miss a dose of Gluconorm SR 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gluconorm

  • Diarrhea
  • Nausea
  • Vomiting
  • Flatulence


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Q. What does Gluconorm SR 500mg Tablet do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Gluconorm SR 500mg Tablet acts in several ways to reduce the increased levels of sugar in blood. Gluconorm SR 500mg Tablet decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Q. Does Gluconorm SR 500mg Tablet cause weight loss?

Yes, Gluconorm SR 500mg Tablet has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Q. What are the benefits of taking Gluconorm SR 500mg Tablet?

Gluconorm SR 500mg Tablet is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Gluconorm SR 500mg Tablet when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Q. Can Gluconorm SR 500mg Tablet make you sleepy?

Gluconorm SR 500mg Tablet usually does not cause sleepiness and is well tolerated. However, the use of Gluconorm SR 500mg Tablet may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Gluconorm SR 500mg Tablet.

Q. How to take Gluconorm SR 500mg Tablet?

Take Gluconorm SR 500mg Tablet with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Gluconorm SR 500mg Tablet with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.


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Pack size  – 15

Pack form  – tablet

Weight  – 14 (gms)

Dimensions  – 6.2 (cm) x 0.1 (cm) x 9.8 (cm)


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 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

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