SKU: AH_CH_HBP_8595 Category:

Generic : Eplerenone (50mg)

Treatment : Hypertension ( High Blood Pressure) , Edema , Heart failure

Pack size  : 10 (Tablet)

Manufacturer : Glenmark Pharmaceuticals Ltd

Made In : INDIA



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Eptus 50 Tablet is a medicine known as a diuretic (water pill). It is mainly used in the treatment of heart failure and high blood pressure. It is also used to reduce swelling (edema) caused by some other conditions.

Eptus 50 Tablet can be taken with or without food, but you should take it, in the same way, each time to get the most benefit. Taking it with food can reduce some side effects and taking it early in the day can prevent you from having to get up at night to go to the toilet. You should keep using this medicine as it has been prescribed, even if you feel well. If you stop taking it, your condition may get worse. If you are being treated for high blood pressure, lifestyle changes such as taking regular exercise and changes to your diet may increase the effectiveness of this medicine.

You should be careful about using Eptus 50 Tablet if you have kidney problems or are unable to urinate. Before taking it, tell your doctor if you have ever had kidney, liver, or heart disease or you are pregnant. Also let your healthcare team know about all other medications you are using as they may affect, or be affected by this medicine. This medicine should only be used if it is clearly needed during pregnancy and while breastfeeding. While using this medicine, you may be advised to limit your intake of salt or salt substitutes, and you should have your blood pressure checked frequently. Some other tests will be done to monitor your progress.


In Treatment of Hypertension (high blood pressure)

Eptus 50 Tablet is generally used in combination with other medicines to control your blood pressure. It works by reducing the amount of water in the body by increasing the flow of urine. This way it lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

In Treatment of Edema

Edema is caused by your body retaining too much water. Eptus 50 Tablet is a diuretic medicine (water pill) that helps get rid of the extra water and electrolytes from your body. It helps relieve symptoms such as swelling in your arms, legs, or abdomen. This will thus help you go about your daily activities more comfortably. Take it regularly and make appropriate lifestyle changes to get maximum benefits.

In Treatment of Heart failure

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Eptus 50 Tablet makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.



Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Eptus 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.



Eptus 50 Tablet is a potassium-sparing diuretic. It works by stopping aldosterone (a natural substance) from increasing your blood pressure. It also reduces the fluid around your heart. This helps improve your heart function after a heart attack and can help prevent heart attacks, strokes or heart failure getting worse.





Eptus 50 Tablet may cause excessive drowsiness with alcohol.


Eptus 50 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Information regarding the use of Eptus 50 Tablet during breastfeeding is not available. Please consult your doctor.


Eptus 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


Eptus 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Eptus 50 Tablet may be needed. Please consult your doctor.
Use of Eptus 50 Tablet is not recommended in patients with severe kidney disease.


Eptus 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Eptus 50 Tablet may be needed. Please consult your doctor.
Use of Eptus 50 Tablet is not recommended in patients with severe liver disease as the data available is limited.






If you miss a dose of Eptus 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Eptus

  • Dizziness
  • Diarrhea
  • Nausea
  • Cough
  • Flu-like symptoms
  • Fatigue
  • Increased potassium level in blood
  • Increased creatinine level in blood
  • Headache


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Q. What does Eptus 50 Tablet do? Is it a beta blocker or a diuretic?

Eptus 50 Tablet is a potassium-sparing diuretic. It is prescribed with other medicines to control increased blood pressure and to treat heart failure in patients who have had a heart attack. It is not a beta blocker but mineralocorticoid receptor blocker.

Q. How long does Eptus 50 Tablet take to work?

Eptus 50 Tablet controls high blood pressure but does not cure it. You may not see any improvement because high blood pressure does not have any symptoms. But, if you get your blood pressure checked, you may notice a change within 2 weeks of starting Eptus 50 Tablet. However, the medicine may take 4 weeks or longer to show its maximum benefits.

Q. Does Eptus 50 Tablet cause erectile dysfunction?

No, Eptus 50 Tablet does not cause erectile dysfunction. Eptus 50 Tablet does not have any effect on fertility, in both males and females.

Q. My blood pressure is now controlled, still the doctor has asked me to continue the treatment. Can I stop Eptus 50 Tablet?

No, you should not stop Eptus 50 Tablet. If your doctor has advised you to continue treatment, keep taking it. Eptus 50 Tablet does not cure blood pressure, but keeps the blood pressure in control. Therefore, keep taking the medicine even if your blood pressure is controlled. Stopping it may make your condition worse and you may have unwanted side effects.

Q. Eptus 50 Tablet is a potassium-sparing diuretic. Does this mean that I will have more potassium in my body? Will it be beneficial for me?

Potassium-sparing diuretic are those medicines which increase the urination without causing any loss in potassium levels. Eptus 50 Tablet allows sodium loss by body in exchange for potassium which is retained. It may result in an increase in the levels of potassium. Therefore, your doctor may monitor your potassium levels continuously. You may need to get it measured before starting Eptus 50 Tablet, within the first week and one month after the start of treatment or after a change in dose. Potassium levels above normal range are not good for you or anyone.

Q. Does Eptus 50 Tablet have any effect on the blood sugar levels?

Although it is not very common, but Eptus 50 Tablet may increase your blood sugar levels. Therefore, it is important that you keep a regular check on your blood sugar levels if you are a diabetic. The use of Eptus 50 Tablet should be avoided in patients who have type 2 diabetes along with some kidney problem in which the patient loses protein (albumin) in very small quantities in urine.

Q. I had been using Losartan for quite some time and was tolerating it well. Now my doctor has prescribed me Eptus 50 Tablet along with Hydrochlorothiazide. I want to know why he just could not add Eptus 50 Tablet with Losartan?

It could be possible that Losartan was not able to control your blood pressure adequately. Therefore, your doctor may have suggested an alternative medicine for blood pressure control (Eptus 50 Tablet), but Eplerenone when taken with Losartan can enhance the chances of raised potassium levels which could be harmful for you. To prevent this rise in potassium levels, the combination of Eptus 50 Tablet with hydrochlorothiazide may have been prescribed.

Q. Is there anything I need to be careful about if I am taking aspirin and have now started Eptus 50 Tablet?

Aspirin may interfere with the working of Eptus 50 Tablet due to which your blood pressure may not get adequately controlled. Aspirin and Eptus 50 Tablet may increase the chances of rise in potassium levels in patients with kidney problems. Therefore, if both are to be used together, keep monitoring your blood pressure and potassium levels.


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Pack size  – 10

pack form  – tablet


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 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

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