SKU: AH_ML_AR_9551 Category:

Generic : Sulfasalazine (500mg)

Treatment : Rheumatoid arthritis, Ulcerative colitis, Crohn’s disease, Ankylosing spondylitis, Psoriatic arthritis,

Pack size : 15 (Tablet)

Manufacturer : Wallace Pharmaceuticals Pvt Ltd

Made In : INDIA



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Sazo 500 Tablet is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease).

Sazo 500 Tablet is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones.

Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.


In Treatment of Rheumatoid arthritis

Sazo 500 Tablet helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

In Treatment of Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Sazo 500 Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Sazo 500 Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

In Treatment of Psoriatic arthritis

Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects some individuals with psoriasis, causing joint pain, swelling, and stiffness alongside skin symptoms. Sazo 500 Tablet has anti-inflammatory properties that help reduce joint pain, swelling, and stiffness. This medicine can also slow down the progression of joint damage associated with PsA. Additionally, it can help improve skin symptoms in individuals with both psoriasis and arthritis.



Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazo 500 Tablet is to be taken with food.



Sazo 500 Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).





It is unsafe to consume alcohol with Sazo 500 Tablet.


Sazo 500 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Sazo 500 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Sazo 500 Tablet does not usually affect your ability to drive.


Sazo 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazo 500 Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.


Sazo 500 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.








If you miss a dose of Sazo 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.



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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sazo

  • Diarrhea
  • Gastrointestinal discomfort
  • Headache
  • Loss of appetite
  • Nausea
  • Oligospermia (low sperm count)
  • Vomiting


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Q. Is Sazo 500 Tablet a steroid or a painkiller?

Sazo 500 Tablet is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn’s disease in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).

Q. What is Sazo 500 Tablet and what is it used for?

Sazo 500 Tablet belongs to a group of medicines called aminosalicylates. It is an anti-inflammatory disease and is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis and Crohn’s disease. In rheumatoid arthritis, it helps prevent damage to the joints and works slowly to reduce swelling and stiffness in your joints.

Q. I have been prescribed Sazo 500 Tablet for rheumatoid arthritis. When can I expect the pain in joints to be better?

Sazo 500 Tablet does not work right away. It takes about 6 to 12 weeks to deliver the full effect.You may start feeling better in 4 weeks after starting Sazo 500 Tablet, but it can vary from person to person and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.

Q. For how long do I need to take Sazo 500 Tablet?

If you are able to tolerate Sazo 500 Tablet which means the side effects do not bother you, then you have to continue Sazo 500 Tablet till the disease remains in remission. It is better to take Sazo 500 Tablet for the prescribed period.

Q. Does the use of Sazo 500 Tablet for the treatment of arthritis affect the kidney function?

Though it is uncommon, Sazo 500 Tablet may affect your kidney function. Therefore, it is important that your kidney function remains normal before you start taking Sazo 500 Tablet. If during treatment with Sazo 500 Tablet your kidney functions become abnormal, you should consult your doctor.

Q. Do I need to get any blood tests done while on Sazo 500 Tablet therapy?

Your doctor will advise you blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver known as enzymes (liver function tests) and urine for protein and blood before you start treatment and at regular intervals.

Q. Can Sazo 500 Tablet affect my fertility?

Decreased sperm count and infertility have been reported in some males. These may disappear once Sazo 500 Tablet is discontinued.

Q. Can I take azathioprine along with Sazo 500 Tablet?

You should avoid using Sazo 500 Tablet with azathioprine since there are chances of decrease in blood cell count, which can be a serious side effect.


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Pack size  – 15

pack form  – Tablet


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 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

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