Generic :  Deflazacort (6mg/5ml)

Treatment : Duchenne muscular dystrophy, Inflammatory & Autoimmune conditions, Treatment of Cancer

Pack size  : 30 Ml  (Syrup)

Manufacturer :  Macleods Pharmaceuticals Pvt Ltd

Made In : INDIA




Defcort Oral Suspension belongs to a group of medicines known as corticosteroids. Its anti-inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.

Give Defcort Oral Suspension to your child orally, either before or after food. Giving it with food helps prevent the risk of developing a stomach upset. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.

It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defcort Oral Suspension can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defcort Oral Suspension can impact both of these.

This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, fluid and electrolyte disturbance, and common cold symptoms. Reach out to your child’s doctor if these side effects appear.

Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.


In Treatment of Duchenne muscular dystrophy(DMD)

Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy, characterized by muscle weakness and atrophy due to the effect of the body’s immune system mechanisms. Defcort Oral Suspension slows the progression of DMD. The exact mechanism by which it acts is unclear, but it is thought to help mediate the condition by suppressing the immune system. For DMD, Defcort Oral Suspension is approved to be used in children above 5 years of age.

In Treatment of Inflammatory conditions

Defcort Oral Suspension gives relief in inflammatory conditions that affect muscles and joints such as arthritis and ankylosing spondylitis. It also helps manage other inflammatory conditions such as asthma, inflammatory bowel disease, uveitis, ulcerative colitis, and allergies. It works by blocking certain chemicals that cause pain and swelling.

In Treatment of Autoimmune conditions

Defcort Oral Suspension gives relief in autoimmune conditions like psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions.

In Treatment of Cancer

Defcort Oral Suspension helps in the treatment of a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It works by suppressing the immune system thereby reducing inflammation around the site of cancer. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain. Moreover, it helps to treat or prevent allergic reactions in cancer patients.


Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Defcort Oral Suspension may be taken with or without food, but it is better to take it at a fixed time.
Avoid Defcort Oral Suspension with salad and vegetable diet.




Defcort Oral Suspension is safe to use in patients with kidney disease. No dose adjustment of Defcort Oral Suspension is recommended.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defcort Oral Suspension to your child.


Defcort Oral Suspension should be used with caution in patients with liver disease. Dose adjustment of Defcort Oral Suspension may be needed. Please consult your doctor.


Do not panic. Unless your child’s doctor has advised a specific regime for your child, give the missed dose as soon as you remember it. Skip the missed dose if it is almost the time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.


Defcort Oral Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Defcort

  • Common cold
  • Increased appetite
  • Weight gain
  • Frequent urge to urinate
  • Cushing syndrome
  • Cough
  • Abnormal hair growth
  • Upper respiratory tract infection
  • Obesity
  • Nasopharyngitis (inflammation of the throat and nasal passages)


Q. Is Defcort Oral Suspension a steroid?

Yes, Defcort Oral Suspension is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defcort Oral Suspension increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

Q. In what conditions should I avoid giving Defcort Oral Suspension to my child?

Avoid giving Defcort Oral Suspension to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defcort Oral Suspension should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

Q. What do I need to know about Defcort Oral Suspension and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defcort Oral Suspension. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defcort Oral Suspension.

Q. How can I store Defcort Oral Suspension at home?

Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.

Q. My child is suffering from a seizure disorder. Is it safe to give Defcort Oral Suspension to my child?

Ans: Prolonged intake of Defcort Oral Suspension can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defcort Oral Suspension.


Pack size  – 30 ml

pack form  – syrup

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