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CELKERAN 2 MG TABLET
Generic : Chlorambucil (2mg)
Treatment : Blood cancer , Hodgkin’s disease
Pack size : 30 (Tablet)
Manufacturer : Celon Laboratories Ltd
Made In : INDIA
PRODUCT INTRODUCTION
Celkeran 2 Tablet is used in the treatment of some cancers of blood and lymphatic system. It may be also used to treat other kinds of cancer, as determined by the doctor. It is used alone or in combination with other cancer medicines.
Celkeran 2 Tablet should be taken empty stomach, or 1 hour before and 2 hours after a meal. But, try to have it at the same time every day for most benefits. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
BENEFITS OF CELKERAN TABLET
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Celkeran 2 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Hodgkin’s disease
Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Celkeran 2 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Take it as prescribed and follow your doctor’s instructions carefully.
HOW TO USE CELKERAN TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Celkeran 2 Tablet is to be taken empty stomach.
HOW CELKERAN TABLET WORKS
Celkeran 2 Tablet is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
SAFETY ADVICE
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Celkeran 2 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Celkeran 2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Celkeran 2 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Celkeran 2 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Celkeran 2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Celkeran 2 Tablet may be needed. Please consult your doctor.
Careful monitoring by a doctor is important as kidney disease patients are at an increased risk of bone marrow depression and inflammation and infections of urinary bladder while taking this medicine.
Careful monitoring by a doctor is important as kidney disease patients are at an increased risk of bone marrow depression and inflammation and infections of urinary bladder while taking this medicine.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Celkeran 2 Tablet in patients with liver disease. Please consult your doctor.
WHAT IF YOU FORGET TO TAKE CELKERAN TABLET?
If you miss a dose of Celkeran 2 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
SIDE EFFECTS
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celkeran
- Anemia (low number of red blood cells)
- Decreased blood cells (red cells, white cells, and platelets)
- Decreased white blood cell count (neutrophils)
- Decreased white blood cell count
- Bone marrow suppression
- Nausea
- Vomiting
- Diarrhea
- Mouth ulcer
FAQ's
Q. How is Celkeran 2 Tablet administered?
Celkeran 2 Tablet is administered orally in tablet form.
Q. Why is Celkeran 2 Tablet toxic to cancer cells/ how does Celkeran 2 Tablet work?
Celkeran 2 Tablet belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.
Q. Does Celkeran 2 Tablet cause hair loss/constipation?
No, hair loss or constipation has not been reported with the use of Celkeran 2 Tablet.
Q. What is Celkeran 2 Tablet used for?
Celkeran 2 Tablet is used to treat some types of blood cancers like Hodgkin’s disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin’s lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom’s macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).
Q. How is Celkeran 2 Tablet excreted?
Celkeran 2 Tablet is metabolized in liver to form nontoxic compounds which are excreted in urine.
Q. Does Celkeran 2 Tablet need to be refrigerated?
Celkeran 2 Tablet has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.
ADDITIONAL INFORMATION
Pack size – 30
pack form – tablet
MORE INFORMATION
Information Leaflet
Always read the patient information leaflet before commencing treatment.
Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.
