SKU: AH_ML_OP_4951 Category:

Generic : Pamidronate (90mg)

Treatment : Osteoporosis, Hypercalcemia

Pack size  : 1 Injection (Vial )

Manufacturer : United Biotech Pvt Ltd

Made In : INDIA



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Biodronate 90mg Injection is used to treat high levels of a mineral called calcium in people who have cancer. It is also used to treat or prevent weakening of the bones. Using this medicine can reduce your risk of breaking bones.

Biodronate 90mg Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Biodronate 90mg Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.



In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Biodronate 90mg Injection is a type of medicine called a bisphosphonate. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is usually given once every year to treat osteoporosis and every two years to prevent it.

You can help improve the strength of you bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

In Hypercalcemia

Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcaemia (high blood calcium levels). It is a serious condition and affects a large number of people with cancer. Biodronate 90mg Injection is a type of medicine called a bisphosphonate. It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body. This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.

Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.



Your doctor or nurse will give you this medicine. Kindly do not self administer.



Biodronate 90mg Injection is a bisphosphonate. It acts by suppressing the activity of osteoclasts, cells that cause the destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.




Consuming alcohol with Biodronate 90mg Injection does not cause any harmful side effects.


Biodronate 90mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

Biodronate 90mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
If you are taking Biodronate 90mg Injection during breastfeeding, monitor the baby’s blood calcium levels during the first two months.


Biodronate 90mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


Biodronate 90mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Biodronate 90mg Injection may be needed. Please consult your doctor.


Biodronate 90mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Biodronate 90mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Biodronate 90mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.






If you miss a dose of Biodronate 90mg Injection, skip it and continue with your normal schedule. Do not double the dose.


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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Biodronate

  • Headache
  • Back pain
  • Musculoskeletal (bone, muscle or joint) pain
  • Heartburn
  • Diarrhea
  • Indigestion


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Q. What does Biodronate 90mg Injection do?

Biodronate 90mg Injection helps in preventing breakdown of the bones. Bone is continuously being broken down and regenerated by special kinds of bone cells by a process called remodelling or turnover. However, conditions like bone stress and bone marrow edema may create pain and imbalance in this daily turnover. Biodronate 90mg Injection acts in the areas with increased bone turnover, decreases this process of breakdown and thereby reduces the pain and discomfort associated with it.

Q. How is Biodronate 90mg Injection administered?

Biodronate 90mg Injection should be administered under the supervision of a doctor or a trained healthcare professional and should not be self-administered. It is given as a 1-2 hour infusion by a drip into a vein in your arm. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Biodronate 90mg Injection.

Q. How often will I be given Biodronate 90mg Injection?

Your dose of Biodronate 90mg Injection will be decided by your doctor depending on your condition. Usually, an individual requires 1-3 doses of Biodronate 90mg Injection.However, the exact dose and its frequency will depend on your illness and how well you respond to the treatment.

Q. Is Biodronate 90mg Injection safe in pregnancy or breastfeeding?

No, Biodronate 90mg Injection may not be safe in pregnancy or breastfeeding. Although Biodronate 90mg Injection does not affect the fertility of women or the sperm count in males, it is best to consult your doctor before taking Biodronate 90mg Injection. In general, avoid Biodronate 90mg Injection if you are pregnant, planning to get pregnant or breastfeeding to avoid any harmful effects on the baby. There is not enough data available to know the exact effect of Biodronate 90mg Injection on the unborn baby or via breast milk. Also, women who are taking Biodronate 90mg Injection are advised to avoid pregnancy after 6 months of completing treatment with Biodronate 90mg Injection.. This is because traces of Biodronate 90mg Injection stays in the bones for long periods of time and may be released during this time which can cause harm to the baby.

Q. Does Biodronate 90mg Injection cause hair loss?

Yes, Biodronate 90mg Injection can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.

Q. Is Biodronate 90mg Injection safe?

Biodronate 90mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

Q. What other lifestyle changes should I make?

To get maximum benefit from Biodronate 90mg Injection, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.


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Pack size  – 1

pack form  – vial


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 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

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