SKU: AH_AB_PU_3669 Category:

Generic : Benzathine penicillin G (500000IU)

Treatment : Bacterial Infections, Syphilis Prevention Of Rheumatic Fever

Pack size  : 1 Injection (Vial)

Manufacturer : Karnataka Antibiotics & Pharmaceuticals Ltd

Made In : INDIA



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Benzathine 500000IU Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in treating sore throat and sexually transmitted diseases like Syphilis. This medicine is also used to prevent some bacterial infections such as Rheumatic fever.

Benzathine 500000IU Injection is a long-acting type of penicillin, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as an injection into the muscle under the supervision of a healthcare professional. It should be used regularly as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.



In Treatment of Bacterial infections

Benzathine 500000IU Injection is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It works by stopping the growth of the bacteria causing the infection. This medicine is given by a doctor or a nurse and should not be self-administered. It usually makes you feel better quite quickly. You must continue the treatment as prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

In Treatment of Syphilis

Syphilis is a bacterial infection usually spread by sexual contact. The disease starts as a painless sore particularly on your genitals, rectum or mouth. If diagnosed in early stages, syphilis can be treated with the use of Benzathine 500000IU Injection, which is an antibiotic that kills the infection causing bacteria and also stops progression of the disease. It is given only by a doctor or nurse into a muscle. Follow the doctor’s instructions carefully to get maximum benefit.

In Prevention of Rheumatic fever

Rheumatic fever is an inflammatory disease caused by the bacteria streptococcus, that results usually die to inadequately treated throat infections or scarlet fever caused by the same microorganisms. Benzathine 500000IU Injection effectively relieves symptoms, controls inflammation and also prevents the disease from returning. If you are allergic to penicillin, tell your doctor before taking it, so you may be treated with some other alternate medicine. If you are using it for the first time, let your doctor know if you notice any signs of allergy such as rash, swelling or any other bothersome side effect.



Your doctor or nurse will give you this medicine. Kindly do not self administer.



Benzathine 500000IU Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.





Consuming alcohol with Benzathine 500000IU Injection does not cause any harmful side effects.


Benzathine 500000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Benzathine 500000IU Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Benzathine 500000IU Injection may cause side effects which could affect your ability to drive.


Benzathine 500000IU Injection should be used with caution in patients with kidney disease. Dose adjustment of Benzathine 500000IU Injection may be needed. Please consult your doctor.


There is limited information available on the use of Benzathine 500000IU Injection in patients with liver disease. Please consult your doctor.



If you miss a dose of Benzathine 500000IU Injection, consult your doctor.



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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Benzathine

  • Rash
  • Allergic reaction
  • Injection site reactions (pain, swelling, redness)


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Q. Can Benzathine 500000IU Injection cause an allergic reaction?

Can Benzathine 500000IU Injection cause an allergic reaction?<br>Yes. Benzathine 500000IU Injection may cause an allergic reaction, although it is rare. Get emergency medical help if you have any of the signs of an allergic reaction, such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Q. What should I discuss with my doctor before receiving Benzathine 500000IU Injection?

Before taking Benzathine 500000IU Injection, you should tell your doctor if you have ever had an allergic reaction to Benzathine 500000IU Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Benzathine 500000IU Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Benzathine 500000IU Injection.

Q. Why does Benzathine 500000IU Injection shot hurt so much?

Benzathine 500000IU Injection is injected deeply into the muscle, usually into the butt muscle, using a lot of fluid used to inject it. Moreover, it is injected slowly which makes it even more painful.

Q. How is Benzathine 500000IU Injection given?

Benzathine 500000IU Injection must be injected slowly and deeply into a muscle of the buttock or hip. Do not inject this medicine near or into an artery, vein, or nerve as it could lead to some serious side effects.

Q. The solution looks discolored. Can I still use Benzathine 500000IU Injection?

No. You should not use Benzathine 500000IU Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.

Q. I feel better now. Can I stop taking Benzathine 500000IU Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Benzathine 500000IU Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Q. Does Benzathine 500000IU Injection treat the flu?

No. Benzathine 500000IU Injection does not treat a viral infection such as the flu or a common cold.


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Pack size  – 1

pack form  – injection


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 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

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